Jan
15

VIVI successfully secured another ICGEB grant for Heart-on-a-Chip

Our Vinmec-VinUni Research Institute of Immunology is celebrating a major achievement! Our project led by Dr. Nguyen Xuan Hung, has been awarded a prestigious grant of EUR 45,000 from the International Centre for Genetic Engineering and Biotechnology (ICGEB).

Selected from 648 applications across 54 countries, this grant is an encouraging recognition of our team’s work. Together with the earlier $150,000 VinUni funding, it provides steady support for continuing our precision medicine efforts in Vietnam.

❤️‍About the Groundbreaking Research: Precision Heart Treatment for Vietnamese Patients

  • We previously generated hiPSC lines from Vietnamese patient with Hypertrophic Cardiomyopathy carrying Vietnamese specific mutations and differentiated them into cardiomyocytes (the muscle cells responsible for the heart’s beating) . Building on that work, we are now developing an advanced multi-lineage Heart-on-a-Chip—a microfluidic system that grow miniature 3D cardiac tissue derived from Vietnamese patients.
  • Key Objectives
  1. Modeling heart diseases using multi-lineage heart-on-a-chip with Vietnamese-specific genetic variants.
  2. Testing cardiac drug for their safety and effectiveness in the our population in order to detect potential cardiotoxicity early on.
  3. Developing innovative therapies, including exosomes-based treatments for ischemia-reperfusion injury
  • Expected Impact & Products The long-term goal is to establish a world-class platform for cardiovascular disease drug testing in Vietnam, making heart treatments more precise and effective for local patients. The project will also significantly reduce the reliance on animal testing and build Vietnam’s capacity in advanced biomedical research by providing hands-on training for young scientists.

Congratulations to our team!